Ketogenic Diet And Medication Combinations
The ketogenic diet is commonly used in conjunction with one of more anticonvulsant medication, and more is being learned about the risks and benefits of these combinations. To begin with, the ketogenic diet does not seem to change the blood levels of common anticonvulsant medications in any significant way. Investigators have measured plasma levels both before and after diet initiation and found no significant differences. . It seems that you dont need to decrease or increase any medications when starting the diet to keep blood levels the same.
Regarding tolerability, valproic acid, topiramate and zonisamide have garnered the most concern, as the side effects of the ketogenic diet and these medications overlap. Traditionally, there has been a perception that valproic acid and the ketogenic diet should not be used together because of the increased risk of side effects such as liver toxicity and pancreatitis. Recent clinical evidence, however, suggests that the use of valproic acid in patients on the ketogenic diet is safe and well tolerated.
Concerns regarding combination therapy with topiramate or zonisamide have been largely based on side effects similar to those seen with the ketogenic diet namely the risk of kidney stones and the development of metabolic acidosis. Despite these concerns, studies show that these medications can be used safely with the ketogenic diet, without an increased risk of stones and only minimal increased risk of symptomatic acidosis .
Will The Keto Diet Interfere With My Medication
I am taking Warfarin and I will always have to take it. Will the Keto diet interfere with my medication?
- Betty Smith asked 3 years ago
- last edited 3 years ago
- You must to post comments
Hi Betty, Im not a medical professional so I cant say for sure but I do not think it would affect the medication but may make you feel better.
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Please first to submit.
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The ketogenic diet has become a buzzworthy diet in the past few years. One of the biggest successes of the keto diet is that it can help many people lose weight. For others, it has helped boost energy levels, improve cholesterol levels, and control blood sugar. However, like all diets, it is essential to talk to your doctor before trying keto, especially if you have a thyroid condition like hypothyroidism. Hereâs why.
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Our group at Johns Hopkins presented a poster at the 2007 American Epilepsy Society meeting looking at this question. Interestingly, those patients taking phenobarbital were less likely to respond to the diet than those patients on other medications over the first few months. There was also a suggestion that zonisamide may work well in conjunction with the diet, although this remains unclear. Hopefully, further research will help elucidate the interaction between the diet and anticonvulsant medications.
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